Protein Radical Formation Resulting from Eosinophil Peroxidase-catalyzed Oxidation of Sulfite

Eosinophil peroxidase (EPO) is an abundant heme protein in eosinophils that catalyzes the formation of cytotoxic oxidants implicated in asthma, allergic inflammatory disorders, and cancer. It is known that some proteins with peroxidase activity (horseradish peroxidase and prostaglandin hydroperoxida...

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Bibliographic Details
Main Authors: Ranguelova, Kalina, Chatterjee, Saurabh, Ehrenshaft, Marilyn, Ramirez, Dario C., Summers, Fiona A., Kadiiska, Maria B., Mason, Ronald P.
Format: Artigo
Language:Inglês
Published: American Society for Biochemistry and Molecular Biology 2010
Subjects:
Enzymology
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC2911282/
https://ncbi.nlm.nih.gov/pubmed/20501663
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M109.069054
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