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The BDNF Val66Met Polymorphism Impairs NMDA Receptor-Dependent Synaptic Plasticity in the Hippocampus

The Val66Met polymorphism in the brain-derived neurotrophic factor (BDNF) gene results in a defect in regulated release of BDNF and affects episodic memory and affective behaviors. However, the precise role of the BDNF Val66Met polymorphism in hippocampal synaptic transmission and plasticity has not...

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Bibliografiske detaljer
Main Authors: Ninan, Ipe, Bath, Kevin G., Dagar, Karishma, Perez-Castro, Rosalia, Plummer, Mark R., Lee, Francis S., Chao, Moses V.
Format: Artigo
Sprog:Inglês
Udgivet: Society for Neuroscience 2010
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC2911131/
https://ncbi.nlm.nih.gov/pubmed/20592208
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1523/JNEUROSCI.1405-10.2010
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