Deficiency of Rac1 Blocks NADPH Oxidase Activation, Inhibits Endoplasmic Reticulum Stress, and Reduces Myocardial Remodeling in a Mouse Model of Type 1 Diabetes

OBJECTIVE: Our recent study demonstrated that Rac1 and NADPH oxidase activation contributes to cardiomyocyte apoptosis in short-term diabetes. This study was undertaken to investigate if disruption of Rac1 and inhibition of NADPH oxidase would prevent myocardial remodeling in chronic diabetes. RESEA...

Ful tanımlama

Kaydedildi:
Detaylı Bibliyografya
Asıl Yazarlar: Li, Jianmin, Zhu, Huaqing, Shen, E, Wan, Li, Arnold, J. Malcolm O., Peng, Tianqing
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: American Diabetes Association 2010
Konular:
Complications
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC2911061/
https://ncbi.nlm.nih.gov/pubmed/20522592
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.2337/db09-1800
Etiketler: Etiketle
Etiket eklenmemiş, İlk siz ekleyin!

Benzer Materyaller