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Rapid functional dissection of genetic networks via tissue-specific transduction and RNAi in mouse embryos
Using ultrasound-guided in utero infections of fluorescently traceable lentiviruses carrying RNAi or Cre recombinase into mouse embryos, we have demonstrated noninvasive, highly efficient selective transduction of surface epithelium, in which progenitors stably incorporate and propagate the desired...
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| Main Authors: | , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2010
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2911018/ https://ncbi.nlm.nih.gov/pubmed/20526348 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/nm.2167 |
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