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A potential regulatory role for mRNA secondary structures within the prothrombin 3′UTR

The distal 3′UTR of prothrombin mRNA exhibits significant sequence heterogeneity reflecting an inexact 3′ cleavage/polyadenylation reaction. This same region encompasses a single-nucleotide polymorphism that enhances the normal post-transcriptional processing of nascent prothrombin transcripts. Both...

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Autori principali: Liu, Xingge, Jiang, Yong, Russell, J. Eric
Natura: Artigo
Lingua:Inglês
Pubblicazione: 2010
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC2910803/
https://ncbi.nlm.nih.gov/pubmed/20553951
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.thromres.2010.04.010
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