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Self-targeting by CRISPR: gene regulation or autoimmunity?
CRISPR/Cas is a recently discovered prokaryotic immune system, which is based on small RNAs (“spacers”) that restrict phage and plasmid infection. It has been hypothesized that CRISPRs can also regulate self gene expression by utilizing spacers that target self genes. By analyzing CRISPRs from 330 o...
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| Main Authors: | , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2010
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2910793/ https://ncbi.nlm.nih.gov/pubmed/20598393 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.tig.2010.05.008 |
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