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Shiga Toxin Increases Formation of Clathrin-Coated Pits through Syk Kinase

Clathrin-dependent endocytosis is a main entry mechanism for the glycolipid-binding Shiga toxin (Stx), although clathrin-independent pathways are also involved. Binding of Stx to its receptor Gb3 not only is essential for Stx retrograde transport to the endoplasmic reticulum and toxicity but also ac...

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Detalhes bibliográficos
Main Authors: Utskarpen, Audrun, Massol, Ramiro, van Deurs, Bo, Lauvrak, Silje Ugland, Kirchhausen, Tomas, Sandvig, Kirsten
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2010
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2910670/
https://ncbi.nlm.nih.gov/pubmed/20668539
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0010944
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