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Large-scale Isolation of Flavonolignans from Silybum marianum (Milk Thistle) Extract Affords New Minor Constituents and Preliminary Structure-Activity Relationships

The gram-scale isolation of the major flavonolignan diastereoisomers from milk thistle (Silybum marianum) extract provided an entré into the isolation of two related analogs that are present in extremely minute quantities. The isolation and structure elucidation of these two new compounds, which we...

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Detalhes bibliográficos
Main Authors: Sy-Cordero, Arlene, Graf, Tyler N., Nakanishi, Yuka, Wani, Mansukh C., Agarwal, Rajesh, Kroll, David J., Oberlies, Nicholas H.
Formato: Artigo
Idioma:Inglês
Publicado em: 2009
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2910627/
https://ncbi.nlm.nih.gov/pubmed/19941262
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1055/s-0029-1240624
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