Interleukin-6 Contributes to Age-Related Alteration of Cytokine Production by Macrophages

Here, we studied in vitro cytokine production by splenic macrophages obtained from young and aged BALB/c wild type (WT) and IL-6 knockout (IL-6 KO) mice. Relative to macrophages obtained from young WT mice given lipopolysaccharide (LPS), those from aged WT mice had decreased production of proinflamm...

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Main Authors: Gomez, Christian R., Karavitis, John, Palmer, Jessica L., Faunce, Douglas E., Ramirez, Luis, Nomellini, Vanessa, Kovacs, Elizabeth J.
Format: Artigo
Jezik:Inglês
Izdano: Hindawi Publishing Corporation 2010
Teme:
Research Article
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC2910493/
https://ncbi.nlm.nih.gov/pubmed/20671912
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1155/2010/475139
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