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Interleukin-6 Contributes to Age-Related Alteration of Cytokine Production by Macrophages

Here, we studied in vitro cytokine production by splenic macrophages obtained from young and aged BALB/c wild type (WT) and IL-6 knockout (IL-6 KO) mice. Relative to macrophages obtained from young WT mice given lipopolysaccharide (LPS), those from aged WT mice had decreased production of proinflam...

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Main Authors: Christian R. Gomez, John Karavitis, Jessica L. Palmer, Douglas E. Faunce, Luis Ramirez, Vanessa Nomellini, Elizabeth J. Kovacs
Formato: Artigo
Idioma:Inglês
Publicado: Wiley 2010-01-01
Series:Mediators of Inflammation
Acceso en liña:http://dx.doi.org/10.1155/2010/475139
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