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Interaction of N-methyl-D-aspartate and group 5 metabotropic glutamate receptors on behavioral flexibility using a novel operant set-shift paradigm

Behavioral flexibility or ‘set-shifting’ refers to the ability to modify ongoing behavior in response to changing goals or environmental contingencies. Impaired behavioral flexibility is associated with disorders such as schizophrenia and addiction. Hypofunction of N-methyl-D-aspartate (NMDA) recept...

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Main Authors: Darrah, Justin M., Stefani, Mark R., Moghaddam, Bita
Format: Artigo
Sprog:Inglês
Udgivet: 2008
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC2910418/
https://ncbi.nlm.nih.gov/pubmed/18469540
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1097/FBP.0b013e3282feb0ac
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