Ezrin tunes T-cell activation by controlling Dlg1 and microtubule positioning at the immunological synapse

T-cell receptor (TCR) signalling is triggered and tuned at immunological synapses by the generation of signalling complexes that associate into dynamic microclusters. Microcluster movement is necessary to tune TCR signalling, but the molecular mechanism involved remains poorly known. We show here th...

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Detaylı Bibliyografya
Asıl Yazarlar: Lasserre, Rémi, Charrin, Stéphanie, Cuche, Céline, Danckaert, Anne, Thoulouze, Maria-Isabel, de Chaumont, Fabrice, Duong, Tarn, Perrault, Nathalie, Varin-Blank, Nadine, Olivo-Marin, Jean-Christophe, Etienne-Manneville, Sandrine, Arpin, Monique, Di Bartolo, Vincenzo, Alcover, Andrés
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: Nature Publishing Group 2010
Konular:
Article
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC2910277/
https://ncbi.nlm.nih.gov/pubmed/20551903
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/emboj.2010.127
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