CIN85 regulates dopamine receptor endocytosis and governs behaviour in mice

Despite extensive investigations of Cbl-interacting protein of 85 kDa (CIN85) in receptor trafficking and cytoskeletal dynamics, little is known about its functions in vivo. Here, we report the study of a mouse deficient of the two CIN85 isoforms expressed in the central nervous system, exposing a f...

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Autors principals: Shimokawa, Noriaki, Haglund, Kaisa, Hölter, Sabine M, Grabbe, Caroline, Kirkin, Vladimir, Koibuchi, Noriyuki, Schultz, Christian, Rozman, Jan, Hoeller, Daniela, Qiu, Chun-Hong, Londoño, Marina B, Ikezawa, Jun, Jedlicka, Peter, Stein, Birgit, Schwarzacher, Stephan W, Wolfer, David P, Ehrhardt, Nicole, Heuchel, Rainer, Nezis, Ioannis, Brech, Andreas, Schmidt, Mirko H H, Fuchs, Helmut, Gailus-Durner, Valerie, Klingenspor, Martin, Bogler, Oliver, Wurst, Wolfgang, Deller, Thomas, de Angelis, Martin Hrabé, Dikic, Ivan
Format: Artigo
Idioma:Inglês
Publicat: Nature Publishing Group 2010
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Article
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC2910270/
https://ncbi.nlm.nih.gov/pubmed/20551902
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/emboj.2010.120
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