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Rate-Dependent Action Potential Alternans in Human Heart Failure Implicate Abnormal Intracellular Calcium Handling

BACKGROUND: Alternans in action potential voltage (APV-ALT) at heart rates <110 beats/min is a novel index to predict ventricular arrhythmias. However, the rate-dependency of APV-ALT and its mechanisms in failing versus non-failing human myocardium are poorly understood. It is hypothesized that A...

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Detalhes bibliográficos
Main Authors: Bayer, Jason D., Narayan, Sanjiv M., Lalani, Gautam G., Trayanova, Natalia A.
Formato: Artigo
Idioma:Inglês
Publicado em: 2010
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2910243/
https://ncbi.nlm.nih.gov/pubmed/20382266
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.hrthm.2010.04.008
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