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Comparison of A2E Cyto- and Phototoxicity with all-trans-Retinal in Human Retinal Pigment Epithelial Cells

All-trans-retinal is the precursor of A2E, a fluorophore within lipofuscin, which accumulates in human retinal pigment epithelial (hRPE) cells and contributes to age-related macular degeneration. Here we have compared the in vitro dark cytotoxicity and visible-light-mediated photoreactivity of all-t...

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Bibliografske podrobnosti
Main Authors: Wielgus, Albert R., Chignell, Colin F., Ceger, Patricia, Roberts, Joan E.
Format: Artigo
Jezik:Inglês
Izdano: 2010
Teme:
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC2910196/
https://ncbi.nlm.nih.gov/pubmed/20497365
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/j.1751-1097.2010.00750.x
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