Arene-Ru(II)-Chloroquine Complexes Interact With DNA, Induce Apoptosis on Human Lymphoid Cell Lines and Display Low Toxicity to Normal Mammalian Cells

The complexes [Ru(η(6)-p-cymene)(CQ)Cl(2)] (1), [Ru(η(6)-benzene)(CQ)Cl(2)] (2), [Ru(η(6)-p-cymene)(CQ)(H(2)O)(2)][BF(4)](2) (3), [Ru(η(6)- p-cymene)(en)(CQ)][PF(6)](2) (4), [Ru(η(6)-p-cymene)(η(6)-CQDP)][BF(4)](2) (5) (CQ = chloroquine base; CQDP = chloroquine diphosphate; en = ethylenediamine) int...

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Bibliografski detalji
Glavni autori: Martínez, Alberto, Rajapakse, Chandima S.K., Varela-Ramírez, Armando, Lema, Carolina, Aguilera, Renato J., Sánchez-Delgado, Roberto A.
Format: Artigo
Jezik:Inglês
Izdano: 2010
Teme:
Article
Online pristup:https://ncbi.nlm.nih.gov/pmc/articles/PMC2910123/
https://ncbi.nlm.nih.gov/pubmed/20605217
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.jinorgbio.2010.05.002
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