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The mechanism of antimalarial action of the ruthenium (II)-chloroquine complex [RuCl(2)(CQ)](2)
The mechanism of antimalarial action of the ruthenium-chloroquine complex [RuCl(2)(CQ)](2) (1), previously shown by us to be active in vitro against CQ-resistant strains of Plasmodium falciparum and in vivo against P. berghei, has been investigated. The complex is rapidly hydrolyzed in aqueous solut...
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| Main Authors: | , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2008
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2409194/ https://ncbi.nlm.nih.gov/pubmed/18305967 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s00775-008-0356-9 |
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