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Reconstitution of Helicobacter pylori VacA toxin from purified components
Helicobacter pylori VacA is a pore-forming toxin that causes multiple alterations in human cells and contributes to the pathogenesis of peptic ulcer disease and gastric cancer. The toxin is secreted by H. pylori as an 88 kDa monomer (p88) consisting of two domains (p33 and p55). While an X-ray cryst...
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| Main Authors: | , , , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2010
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2910095/ https://ncbi.nlm.nih.gov/pubmed/20527875 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/bi100618g |
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