Structure of the FoxM1 DNA-recognition domain bound to a promoter sequence

FoxM1 is a member of the Forkhead family of transcription factors and is implicated in inducing cell proliferation and some forms of tumorigenesis. It binds promoter regions with a preference for tandem repeats of a consensus ‘TAAACA’ recognition sequence. The affinity of the isolated FoxM1 DNA-bind...

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Bibliographic Details
Main Authors: Littler, D. R., Alvarez-Fernández, M., Stein, A., Hibbert, R. G., Heidebrecht, T., Aloy, P., Medema, R. H., Perrakis, A.
Format: Artigo
Language:Inglês
Published: Oxford University Press 2010
Subjects:
Structural Biology
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC2910063/
https://ncbi.nlm.nih.gov/pubmed/20360045
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/nar/gkq194
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