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Processive translocation mechanism of the human Bloom’s syndrome helicase along single-stranded DNA

BLM, one of the human RecQ helicases, plays a fundamental role in homologous recombination-based error-free DNA repair pathways, which require its translocation and DNA unwinding activities. Although translocation is essential in vivo during DNA repair processes and it provides a framework for more...

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Bibliografiske detaljer
Main Authors: Gyimesi, Máté, Sarlós, Kata, Kovács, Mihály
Format: Artigo
Sprog:Inglês
Udgivet: Oxford University Press 2010
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC2910040/
https://ncbi.nlm.nih.gov/pubmed/20211839
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/nar/gkq145
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