Evidence that MEK1 positively promotes interhomologue double-strand break repair

During meiosis there is an imperative to create sufficient crossovers for homologue segregation. This can be achieved during repair of programmed DNA double-strand breaks (DSBs), which are biased towards using a homologue rather than sister chromatid as a repair template. Various proteins contribute...

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Bibliographic Details
Main Authors: Terentyev, Yaroslav, Johnson, Rebecca, Neale, Matthew J., Khisroon, Muhammad, Bishop-Bailey, Anna, Goldman, Alastair S. H.
Format: Artigo
Language:Inglês
Published: Oxford University Press 2010
Subjects:
Genome Integrity, Repair and Replication
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC2910038/
https://ncbi.nlm.nih.gov/pubmed/20223769
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/nar/gkq137
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