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Minor resistant variants in nevirapine-exposed infants may predict virologic failure on nevirapine-containing ART

BACKGROUND: Single-dose nevirapine (sdNVP) is widely used to prevent mother-to-child transmission (PMTCT) of HIV-1. This may result in NVP resistance in both mother and infant. The significance of low levels of NVP resistance mutations in infants treated with NVP-containing antiretroviral treatment...

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Autori principali: MacLeod, Iain J., Rowley, Christopher F., Thior, Ibou, Wester, Carolyn, Makhema, Joseph, Essex, Max, Lockman, Shahin
Natura: Artigo
Lingua:Inglês
Pubblicazione: 2010
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC2909836/
https://ncbi.nlm.nih.gov/pubmed/20427228
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.jcv.2010.03.017
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