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Rescue of Renal Hypoplasia and Cystic Dysplasia in Bcl-2 −/− Mice Expressing Bcl-2 in Ureteric Bud Derived Epithelia
Bcl-2 is the founding member of a family of proteins that influence apoptosis. Loss of bcl-2 results in renal hypoplasia/cystic dysplasia at birth. Here we examined whether reexpression of bcl-2 throughout the ureteric bud and its derived epithelia would restore a normal renal phenotype in bcl-2 −/−...
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| Main Authors: | , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2008
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2909767/ https://ncbi.nlm.nih.gov/pubmed/18729219 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/dvdy.21678 |
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