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Peroxynitrite Increases Protein Phosphatase Activity and Promotes the Interaction of Phospholamban with Protein Phosphatase 2a in the Myocardium

High levels of peroxynitrite have been shown to decrease cardiomyocyte contraction through a reduction in phospholamban (PLB) phosphorylation. However, previous reports did not examine the direct effect of peroxynitrite on protein phosphatase activity in the myocardium or the role of specific phosph...

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Autori principali: Kohr, Mark J, Davis, Jonathan P, Ziolo, Mark T
Natura: Artigo
Lingua:Inglês
Pubblicazione: 2009
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC2909675/
https://ncbi.nlm.nih.gov/pubmed/20664715
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.niox.2009.01.003
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