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NMR Structure Determination for Larger Proteins Using Backbone-Only Data
Conventional protein structure determination from nuclear magnetic resonance data relies heavily on side-chain proton-proton distances. The necessary side-chain resonance assignment, however, is labor intensive and prone to error. Here we show that structures can be accurately determined without NMR...
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| Main Authors: | , , , , , , , , , , , , , |
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| Format: | Artigo |
| Jezik: | Inglês |
| Izdano: |
2010
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| Teme: | |
| Online dostop: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2909653/ https://ncbi.nlm.nih.gov/pubmed/20133520 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1126/science.1183649 |
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