NMR Structure Determination for Larger Proteins Using Backbone-Only Data

Conventional protein structure determination from nuclear magnetic resonance data relies heavily on side-chain proton-proton distances. The necessary side-chain resonance assignment, however, is labor intensive and prone to error. Here we show that structures can be accurately determined without NMR...

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Bibliografiset tiedot
Päätekijät: Raman, Srivatsan, Lange, Oliver F., Rossi, Paolo, Tyka, Michael, Wang, Xu, Aramini, James, Liu, Gaohua, Ramelot, Theresa, Eletsky, Alexander, Szyperski, Thomas, Kennedy, Michael, Prestegard, James, Montelione, Gaetano T., Baker, David
Aineistotyyppi: Artigo
Kieli:Inglês
Julkaistu: 2010
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Article
Linkit:https://ncbi.nlm.nih.gov/pmc/articles/PMC2909653/
https://ncbi.nlm.nih.gov/pubmed/20133520
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1126/science.1183649
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