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Signatures of RNA binding proteins globally coupled to effective microRNA target sites

MicroRNAs (miRNAs) and small interfering RNAs (siRNAs), bound to Argonaute proteins (RISC), destabilize mRNAs through base-pairing with the mRNA. However, the gene expression changes after perturbations of these small RNAs are only partially explained by predicted miRNA/siRNA targeting. Targeting ma...

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Autori principali: Jacobsen, Anders, Wen, Jiayu, Marks, Debora S., Krogh, Anders
Natura: Artigo
Lingua:Inglês
Pubblicazione: Cold Spring Harbor Laboratory Press 2010
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC2909566/
https://ncbi.nlm.nih.gov/pubmed/20508147
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1101/gr.103259.109
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