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Role of protein kinase C in the TBT-induced inhibition of lytic function and MAPK activation in human natural killer cells

Human natural killer (NK) cells are lymphocytes that destroy tumor and virally infected cells. Previous studies have shown that exposures of NK cells to tributyltin (TBT) greatly diminish their ability to destroy tumor cells (lytic function) while activating mitogen-activated protein kinases (MAPK)...

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Detalhes bibliográficos
Main Authors: Abraha, Abraham B., Rana, Krupa, Whalen, Margaret M.
Formato: Artigo
Idioma:Inglês
Publicado em: 2010
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2909453/
https://ncbi.nlm.nih.gov/pubmed/20390410
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s00244-010-9520-7
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