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The role of p44/42 activation in tributyltin- induced inhibition of human natural killer cells: Effects of MEK inhibitors

Destruction of tumor cells is a key function of NK cells. Previous studies have shown that tributyltin (TBT) can significantly reduce the lytic function of the human NK cells with accompanying increases in the phosphorylation (activation) states of the mitogen activated protein kinases (MAPKs), p44/...

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Detalhes bibliográficos
Main Authors: Abraha, Abraham B., Whalen, Margaret M.
Formato: Artigo
Idioma:Inglês
Publicado em: 2009
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2642538/
https://ncbi.nlm.nih.gov/pubmed/18989867
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/jat.1397
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