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Human metabolites of brevetoxin PbTx-2: Identification and confirmation of structure
Four metabolites were identified upon incubation of brevetoxin (PbTx-2) with human liver microsomes. Chemical transformation of PbTx-2 confirmed the structures of three known metabolites BTX-B5, PbTx-9 and 41, 43-dihydro-BTX-B5 and a previously unknown metabolite, 41, 43-dihydro-PbTx-2. These metabo...
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| Main Authors: | , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2010
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2909374/ https://ncbi.nlm.nih.gov/pubmed/20600229 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.toxicon.2010.06.007 |
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