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Coagulation Procofactor Activation by Factor Xla

BACKGROUND: In the extrinsic pathway, the essential procofactors factor V (fV) and factor VIII (fVIII) are activated to fVIIIa and fVa by thrombin. In the contact pathway and its clinical diagnostic test, the activated partial thromboplastin time assay (aPTT), the sources of procofactor activation a...

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Détails bibliographiques
Auteurs principaux: Whelihan, Matthew F., Orfeo, Thomas, Gissel, Matthew T., Mann, Kenneth G.
Format: Artigo
Langue:Inglês
Publié: 2010
Sujets:
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC2909362/
https://ncbi.nlm.nih.gov/pubmed/20456758
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/j.1538-7836.2010.03899.x
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