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Coagulation Procofactor Activation by Factor Xla

BACKGROUND: In the extrinsic pathway, the essential procofactors factor V (fV) and factor VIII (fVIII) are activated to fVIIIa and fVa by thrombin. In the contact pathway and its clinical diagnostic test, the activated partial thromboplastin time assay (aPTT), the sources of procofactor activation a...

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Bibliografiske detaljer
Main Authors: Whelihan, Matthew F., Orfeo, Thomas, Gissel, Matthew T., Mann, Kenneth G.
Format: Artigo
Sprog:Inglês
Udgivet: 2010
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC2909362/
https://ncbi.nlm.nih.gov/pubmed/20456758
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/j.1538-7836.2010.03899.x
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