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Coagulation Procofactor Activation by Factor Xla

BACKGROUND: In the extrinsic pathway, the essential procofactors factor V (fV) and factor VIII (fVIII) are activated to fVIIIa and fVa by thrombin. In the contact pathway and its clinical diagnostic test, the activated partial thromboplastin time assay (aPTT), the sources of procofactor activation a...

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Detalhes bibliográficos
Main Authors: Whelihan, Matthew F., Orfeo, Thomas, Gissel, Matthew T., Mann, Kenneth G.
Formato: Artigo
Idioma:Inglês
Publicado em: 2010
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2909362/
https://ncbi.nlm.nih.gov/pubmed/20456758
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/j.1538-7836.2010.03899.x
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