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Coagulation Procofactor Activation by Factor Xla

BACKGROUND: In the extrinsic pathway, the essential procofactors factor V (fV) and factor VIII (fVIII) are activated to fVIIIa and fVa by thrombin. In the contact pathway and its clinical diagnostic test, the activated partial thromboplastin time assay (aPTT), the sources of procofactor activation a...

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Bibliographic Details
Main Authors: Whelihan, Matthew F., Orfeo, Thomas, Gissel, Matthew T., Mann, Kenneth G.
Format: Artigo
Language:Inglês
Published: 2010
Subjects:
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC2909362/
https://ncbi.nlm.nih.gov/pubmed/20456758
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/j.1538-7836.2010.03899.x
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