MAP kinase phosphatase-1 deficiency impairs skeletal muscle regeneration and exacerbates muscular dystrophy

In skeletal muscle, the mitogen-activated protein kinase (MAPK) phosphatase-1 (MKP-1) is a critical negative regulator of the MAPKs. Since the MAPKs have been reported to be both positive and negative for myogenesis, the physiological role of MKP-1 in skeletal muscle repair and regeneration has rema...

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Detalhes bibliográficos
Main Authors: Shi, Hao, Boadu, Emmanuel, Mercan, Fatih, Le, Annie M., Flach, Rachel J. Roth, Zhang, Lei, Tyner, Kristina J., Olwin, Bradley B., Bennett, Anton M.
Formato: Artigo
Idioma:Inglês
Publicado em: The Federation of American Societies for Experimental Biology 2010
Assuntos:
Research Communications
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2909286/
https://ncbi.nlm.nih.gov/pubmed/20371627
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1096/fj.09-150045
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