WNT4 is required for normal ovarian follicle development and female fertility

To study the role of WNT4 in the postnatal ovary, a mouse strain bearing a floxed Wnt4 allele was created and mated to the Amhr2(tm3(cre)Bhr) strain to target deletion of Wnt4 to granulosa cells. Wnt4(flox/−);Amhr2(tm3(cre)Bhr/+) mice had reduced ovary weights and produced smaller litters (P<0.05...

Celý popis

Uloženo v:
Podrobná bibliografie
Hlavní autoři: Boyer, Alexandre, Lapointe, Évelyne, Zheng, Xiaofeng, Cowan, Robert G., Li, Huaiguang, Quirk, Susan M., DeMayo, Francesco J., Richards, JoAnne S., Boerboom, Derek
Médium: Artigo
Jazyk:Inglês
Vydáno: The Federation of American Societies for Experimental Biology 2010
Témata:
Research Communications
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC2909279/
https://ncbi.nlm.nih.gov/pubmed/20371632
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1096/fj.09-145789
Tagy: Přidat tag
Žádné tagy, Buďte první, kdo otaguje tento záznam!

Podobné jednotky