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Effects of GCK, GCKR, G6PC2 and MTNR1B Variants on Glucose Metabolism and Insulin Secretion

BACKGROUND: Single nucleotide polymorphisms (SNPs) from GCK, GCKR, G6PC2 and MTNR1B were found to modulate the fasting glucose levels. The current study aimed to replicate this association in the Chinese population and further analyze their effects on biphasic insulin secretion. METHODS/PRINCIPAL FI...

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Detalhes bibliográficos
Main Authors: Hu, Cheng, Zhang, Rong, Wang, Congrong, Yu, Weihui, Lu, Jingyi, Ma, Xiaojing, Wang, Jie, Jiang, Feng, Tang, Shanshan, Bao, Yuqian, Xiang, Kunsan, Jia, Weiping
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2010
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2909258/
https://ncbi.nlm.nih.gov/pubmed/20668700
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0011761
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