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Porphyromonas gingivalis Resistance to Polymyxin B Is Determined by the Lipid A 4′-Phosphatase, PGN_0524

AIM: To elucidate the genetic basis for the pronounced resistance that the oral pathogen, Porphyromonas gingivalis (P. gingivalis), exhibits towards the cationic antimicrobial peptide, polymyxin B. METHODOLOGY: A genetic screen of P. gingivalis clones generated by a Tn4400′-based random insertion mu...

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Detalhes bibliográficos
Main Authors: Coats, Stephen R, To, Thao T, Jain, Sumita, Braham, Pamela H, Darveau, Richard P
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group 2009
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2909122/
https://ncbi.nlm.nih.gov/pubmed/20657724
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4248/IJOS.09062
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