Deficiency of Pten accelerates mammary oncogenesis in MMTV-Wnt-1 transgenic mice
BACKGROUND: Germline mutations in the tumor suppressor PTEN predispose human beings to breast cancer, and genetic and epigenetic alterations of PTEN are also detected in sporadic human breast cancer. Germline Pten mutations in mice lead to the development of a variety of tumors, but mammary carcinom...
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| Publicado no: | BMC Mol Biol |
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| Principais autores: | , , , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
BMC
2001
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC29091/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/11178110/ https://ncbi.nlm.nih.govhttps://doi.org/10.1186/1471-2199-2-2 |
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