Aldose Reductase Gene Polymorphisms and Diabetic Retinopathy Susceptibility

OBJECTIVE: Aldose reductase (ALR) is involved in diabetic microvascular damage via the polyol pathway. A recent meta-analysis found genetic variation in the ALR gene (AKR1B1) to be significantly associated with diabetic retinopathy (DR). We investigated the genetic association of AKR1B1 with DR. RES...

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Detalhes bibliográficos
Main Authors: Abhary, Sotoodeh, Burdon, Kathryn P., Laurie, Kate J., Thorpe, Stacey, Landers, John, Goold, Lucy, Lake, Stewart, Petrovsky, Nikolai, Craig, Jamie E.
Formato: Artigo
Idioma:Inglês
Publicado em: American Diabetes Association 2010
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Original Research
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2909072/
https://ncbi.nlm.nih.gov/pubmed/20424224
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.2337/dc09-1893
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