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Inverse relationship between seizure expression and extrasynaptic NMDAR function following chronic NMDAR inhibition

We showed previously that electrographic seizures involving dentate granule cells in organotypic hippocampal slice cultures were dramatically reduced following chronic treatment with the NR2B-selective antagonist, Ro25,6981, but were increased following chronic treatment with the high-affinity compe...

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Autores principales: Bausch, Suzanne B., He, Shuijin, Dong, Yu
Formato: Artigo
Lenguaje:Inglês
Publicado: 2010
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Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC2909021/
https://ncbi.nlm.nih.gov/pubmed/20618412
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/j.1528-1167.2010.02621.x
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