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NF-κB activation enhances cell death by antimitotic drugs in human prostate cancer cells

BACKGROUND: NF-κB is a transcription factor that promotes inhibition of apoptosis and resistance to chemotherapy. It is commonly believed that inhibition of NF-κB activity can increase sensitivity of cancer cells to chemotherapy. However, there is evidence that NF-κB activation can sensitize cells t...

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Autori principali: Parrondo, Ricardo, Pozas, Alicia de las, Reiner, Teresita, Rai, Priyamvada, Perez-Stable, Carlos
Natura: Artigo
Lingua:Inglês
Pubblicazione: BioMed Central 2010
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC2908581/
https://ncbi.nlm.nih.gov/pubmed/20618955
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1476-4598-9-182
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