Mcl-1 protects prostate cancer cells from cell death mediated by chemotherapy-induced DNA damage

The anti-apoptotic protein Mcl-1 is highly expressed in castration-resistant prostate cancer (CRPC), resulting in resistance to apoptosis and association with poor prognosis. Although predominantly localized in the cytoplasm, there is evidence that Mcl-1 exhibits nuclear localization where it is tho...

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Detalhes bibliográficos
Publicado no:Oncoscience
Main Authors: Reiner, Teresita, de las Pozas, Alicia, Parrondo, Ricardo, Palenzuela, Deanna, Cayuso, William, Rai, Priyamvada, Perez-Stable, Carlos
Formato: Artigo
Idioma:Inglês
Publicado em: Impact Journals LLC 2015
Assuntos:
Research Paper
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4580064/
https://ncbi.nlm.nih.gov/pubmed/26425662
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