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Toll-like receptor 7 and 9 defects in common variable immunodeficiency
BACKGROUND: Common variable immunodeficiency (CVID) is characterized by hypogammaglobulinemia, reduced numbers of peripheral blood isotype-switched memory B cells, and loss of plasma cells. OBJECTIVE: Because Toll-like receptor (TLR) activation of B cells can initiate and potentially sustain normal...
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| Main Authors: | , , , , , , |
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| Format: | Artigo |
| Sprog: | Inglês |
| Udgivet: |
2009
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| Fag: | |
| Online adgang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2908501/ https://ncbi.nlm.nih.gov/pubmed/19592080 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.jaci.2009.05.019 |
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