Toll-like receptor 7 and 9 defects in common variable immunodeficiency

BACKGROUND: Common variable immunodeficiency (CVID) is characterized by hypogammaglobulinemia, reduced numbers of peripheral blood isotype-switched memory B cells, and loss of plasma cells. OBJECTIVE: Because Toll-like receptor (TLR) activation of B cells can initiate and potentially sustain normal...

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Main Authors: Yu, Joyce E., Knight, Adina K., Radigan, Lin, Marron, Thomas U., Zhang, Li, Sanchez-Ramón, Silvia, Cunningham-Rundles, Charlotte
Format: Artigo
Jezik:Inglês
Izdano: 2009
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Article
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC2908501/
https://ncbi.nlm.nih.gov/pubmed/19592080
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.jaci.2009.05.019
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