B-cell homeostasis requires complementary CD22 and BLyS/BR3 survival signals

Peripheral B-cell numbers are tightly regulated by homeostatic mechanisms that influence the transitional and mature B-cell compartments and dictate the size and clonotypic diversity of the B-cell repertoire. B-lymphocyte stimulator (BLyS, a trademark of Human Genome Sciences, Inc.) plays a key role...

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Hlavní autoři: Smith, Susan H., Haas, Karen M., Poe, Jonathan C., Yanaba, Koichi, Ward, Christopher D., Migone, Thi-Sau, Tedder, Thomas F.
Médium: Artigo
Jazyk:Inglês
Vydáno: Oxford University Press 2010
Témata:
Original Research Papers
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC2908476/
https://ncbi.nlm.nih.gov/pubmed/20513733
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/intimm/dxq055
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