Association of CR1, CLU and PICALM with Alzheimer's disease in a cohort of clinically characterized and neuropathologically verified individuals

In this study, we assess 34 of the most replicated genetic associations for Alzheimer's disease (AD) using data generated on Affymetrix SNP 6.0 arrays and imputed at over 5.7 million markers from a unique cohort of over 1600 neuropathologically defined AD cases and controls (1019 cases and 591...

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Hauptverfasser: Corneveaux, Jason J., Myers, Amanda J., Allen, April N., Pruzin, Jeremy J., Ramirez, Manuel, Engel, Anzhelika, Nalls, Michael A., Chen, Kewei, Lee, Wendy, Chewning, Kendria, Villa, Stephen E., Meechoovet, Hunsar B., Gerber, Jill D., Frost, Danielle, Benson, Hollie L., O'Reilly, Sean, Chibnik, Lori B., Shulman, Joshua M., Singleton, Andrew B., Craig, David W., Van Keuren-Jensen, Kendall R., Dunckley, Travis, Bennett, David A., De Jager, Philip L., Heward, Christopher, Hardy, John, Reiman, Eric M., Huentelman, Matthew J.
Format: Artigo
Sprache:Inglês
Veröffentlicht: Oxford University Press 2010
Schlagworte:
Association Studies Articles
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC2908469/
https://ncbi.nlm.nih.gov/pubmed/20534741
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/hmg/ddq221
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