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Intraislet production of GLP-1 by activation of prohormone convertase 1/3 in pancreatic α-cells in mouse models of β-cell regeneration

The islet of Langerhans is a highly vascularized micro-organ consisting of not only β-cells but multiple cell types such as α-, delta-, pancreatic polypeptide- and epsilon-cells that work together to regulate glucose homeostatis. We have recently proposed a new model of the neonatal islet formation...

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Main Authors: Kilimnik, German, Kim, Abraham, Steiner, Donald F., Friedman, Theodore C., Hara, Manami
Format: Artigo
Jezik:Inglês
Izdano: 2010
Teme:
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC2908328/
https://ncbi.nlm.nih.gov/pubmed/20657753
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