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The Matrix Metalloproteinase Inhibitor, CTS-1027, Attenuates Liver Injury and Fibrosis in the Bile Duct-Ligated Mouse
Excessive matrix metalloproteinase (MMP) activity has been implicated in the pathogenesis of acute and chronic liver injury. CTS-1027 is a MMP inhibitor, which has previously been studied in humans as an anti-arthritic agent. Thus, our aim was to assess if CTS-1027 is hepato-protective and anti-fibr...
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| Main Authors: | , , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2009
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2908315/ https://ncbi.nlm.nih.gov/pubmed/19624765 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/j.1872-034X.2009.00541.x |
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