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The Matrix Metalloproteinase Inhibitor, CTS-1027, Attenuates Liver Injury and Fibrosis in the Bile Duct-Ligated Mouse

Excessive matrix metalloproteinase (MMP) activity has been implicated in the pathogenesis of acute and chronic liver injury. CTS-1027 is a MMP inhibitor, which has previously been studied in humans as an anti-arthritic agent. Thus, our aim was to assess if CTS-1027 is hepato-protective and anti-fibr...

وصف كامل

محفوظ في:
التفاصيل البيبلوغرافية
المؤلفون الرئيسيون: Kahraman, Alisan, Bronk, Steven F., Cazanave, Sophie, Werneburg, Nathan W., Mott, Justin L., Contreras, Patricia C., Gores, Gregory J.
التنسيق: Artigo
اللغة:Inglês
منشور في: 2009
الموضوعات:
الوصول للمادة أونلاين:https://ncbi.nlm.nih.gov/pmc/articles/PMC2908315/
https://ncbi.nlm.nih.gov/pubmed/19624765
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/j.1872-034X.2009.00541.x
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