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Molecular Mechanisms of Lipotoxicity in Nonalcoholic Fatty Liver Disease
Nonalcoholic fatty liver disease (NAFLD) is characterized by insulin resistance, which results in elevated serum concentration of free fatty acids (FFAs). Circulating FFAs provide the substrate for triacylglycerol formation in the liver, and may also be directly cytotoxic. Hepatocyte apoptosis is a...
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| Main Authors: | , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2008
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2908270/ https://ncbi.nlm.nih.gov/pubmed/18956292 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1055/s-0028-1091980 |
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