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Molecular Mechanisms of Lipotoxicity and Glucotoxicity in Nonalcoholic Fatty Liver Disease

The exposure of hepatocytes to high concentrations of lipids and carbohydrates and the ensuing hepatocellular injury are termed lipotoxicity and glucotoxicity, respectively. A common denominator is metabolic derangement, especially in regards to intracellular energy homeostasis, which is brought on...

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Detalhes bibliográficos
Publicado no:Metabolism
Main Authors: Mota, Manoela, Banini, Bubu A., Cazanave, Sophie C., Sanyal, Arun J.
Formato: Artigo
Idioma:Inglês
Publicado em: 2016
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4931958/
https://ncbi.nlm.nih.gov/pubmed/26997538
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.metabol.2016.02.014
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