R5 Clade C SHIV Strains with Tier 1 or 2 Neutralization Sensitivity: Tools to Dissect Env Evolution and to Develop AIDS Vaccines in Primate Models

BACKGROUND: HIV-1 clade C (HIV-C) predominates worldwide, and anti-HIV-C vaccines are urgently needed. Neutralizing antibody (nAb) responses are considered important but have proved difficult to elicit. Although some current immunogens elicit antibodies that neutralize highly neutralization-sensitiv...

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Autori principali: Siddappa, Nagadenahalli B., Watkins, Jennifer D., Wassermann, Klemens J., Song, Ruijiang, Wang, Wendy, Kramer, Victor G., Lakhashe, Samir, Santosuosso, Michael, Poznansky, Mark C., Novembre, Francis J., Villinger, François, Else, James G., Montefiori, David C., Rasmussen, Robert A., Ruprecht, Ruth M.
Natura: Artigo
Lingua:Inglês
Pubblicazione: Public Library of Science 2010
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Research Article
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC2908149/
https://ncbi.nlm.nih.gov/pubmed/20657739
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0011689
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